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Translational Research:
The George Mason University and Inova Health System Partnership
Pepper Hamilton LLP
Overview
The Center for Applied Proteomics and Molecular Medicine, formed by Drs. Liotta and Petricoin, is one cornerstone of a unique partnership between George Mason and Inova Health System. "The George Mason University-Inova Health System Translational Research Centers," a joint initiative to coordinate multiple programs to implement proteomics, nanotechnology, and genomics research into the diagnosis and treatment of cancer, metabolic syndromes, cardiopulmonary, neurodegenerative, and liver diseases. This initiative comprises the research efforts of three shared centers: the Center for Applied Proteomics and Molecular Medicine; the Center for Biomedical Genomics; and the Center for the Study of Genomics of Liver Diseases. Inova and George Mason have combined efforts to recruit internationally renowned basic scientists, such as Drs. Liotta and Petricoin, to work closely with top-notch clinical investigators.
Research in the Proteomics Center will focus on the discovery and identification of biomarkers-biological indicators of cellular function in body fluids-for early disease detection and risk assessment, and the analysis of molecular pathway function in diseased tissue to determine individualized and targeted treatment for patients. Results of the research will then be translated directly into patient management and care through clinical research and innovative clinical trials, with a vision toward creating a new paradigm to personalize medical treatment, resulting in a positive impact on public health.
Speakers Dr. Lance Liotta, Co-Director
Center for Applied Proteomics and Molecular Medicine
George Mason University
 Dr. Liotta joined the faculty of George Mason University on May 15, 2005. Prior to this, he was Chief of the Laboratory of Pathology at NCI's Center for Cancer Research since 1982. Dr. Liotta also served as chief of the Center's Tumor Invasion and Metastases Section and Chaired the National Institutes of Health Radiation Safety Committee. He earned his medical degree from Case Western Reserve Medical School and is licensed to practice medicine in the state of Maryland. Dr. Liotta also holds a doctoral degree in biomedical engineering from Case Western Reserve University.
Dr. Emanuel F. Petricoin, Co-Director
Center for Applied Proteomics and Molecular Medicine
George Mason University
 Dr. Emanual Petricoin III was appointed to the faculty of George Mason University on April 1, 2005. Prior to this, he joined the FDA in 1993, following a three-year postgraduate fellowship with the agency. He was Senior Investigator in the Office of Cell Tissue and Gene Therapies in the Center for Biologics Evaluation and Research. Dr. Petricoin holds a doctorate in microbiology from the University of Maryland at College Park.
Daniele Struppa, Ph.D.
Dean for the College of Arts and Sciences
George Mason University
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